Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p133 | (1) | WCRB2014

The effect of bisphenol A on Notch signaling pathway in the follicular development of neonatal rat ovary

Altunbas Korhan , Celik Sefa , Yagci Artay , Akkaya Ozlem Ozden

Introduction: Neonatal exposure to bisphenol A (BPA) can impair reproductive physiology, but the specific mechanisms by which this occurs remain largely unknown. We aimed to study whether mRNA levels of Notch receptor and ligands are altered following BPA treatment during postnatal days.Materials and methods: Neonatal rats were divided into two main groups as groups I and II according to treatment time intervals consisting of postnatal day (P)0–P3 a...

ra0001p140 | (1) | WCRB2014

The effects of bisphenol A in in vitro neonatal rat ovary

Altunbas Korhan , Yagci Artay , Celik Sefa , Akkaya Ozlem Ozden , Zik Berrin

Introduction: Neonatal bisphenol A (BPA) exposures affect the developing reproductive tract of females, several distinct stages of oogenesis in the developing ovary. Notch signaling also plays an important role during oogenesis. We aimed to explain whether mRNA levels of Notch receptor and ligands are altered following BPA treatment during neonatal days in vitro.Materials and methods: Wistar rats were sacrificed and ovaries were isolated on post...